Modelling of a Fed-Batch Fermentation Process

Fed-Batch Production of a Fermented Beverage Containing Vitamin B12

Production of fermented functional foods containing micronutrients is required for their health beneficial properties. The impact of 11 process variables on vitamin B12 production in a dairy beverage containing propionic acid was investigated. Propionibacterium freudenreichii ssp. shermanii was applied in a 3-l fermentor in the fed-batch fermentation system. The most suitable conditions for...

Evaluation of Heat Induction Strategy for Recombinant Human Growth Hormone Expression in Fed-Batch Fermentation

Intercriteria Analysis for Identification of Escherichia Coli Fed- Batch Mathematical Model

Escherichia coli produces insulin, interferons, growth factors, exoand endoproducts, e.g. enzymes, etc. In this paper we present a new approach for multicriteria decision making – InterCriteria Analysis to mathematical modelling of a fermentation process. It is based on the apparatus of index matrices and intuitionistic fuzzy sets. The approach for multicriteria analysis makes it possible to co...

A Mathematical Modelling to Predict Rhamnolipid Production by Pseudomonas aeruginosa under Nitrogen Limiting Fed-Batch Fermentation

In this study, a mathematical model was proposed and the accuracy of this model was assessed to predict the growth of Pseudomonas aeruginosa and rhamnolipid production under nitrogen limiting (sodium nitrate) fed-batch fermentation. All of the parameters used in this model were achieved individually without using any data from the literature. The overall growth kinetic of the strain was evaluat...

Batch-to-Batch Iterative Learning Control of a Fed-batch Fermentation Process Using Incrementally Updated Models

Batch-to-batch iterative learning control of a fed-batch fermentation process using batchwise linearised models identified from process operation data is presented in this paper. Due to model-plant mismatches and the present of unknown disturbances, off-line calculated control policy may not be optimal when implemented to the real process. The repetitive nature of batch process allows informati...

Modeling and optimal control of a nonlinear dynamical system in microbial fed-batch fermentation

The mathematical model and optimal control of microbial fed-batch fermentation is considered in this paper. Since it is decisive for increasing the productivity of 1,3propanediol (1,3-PD) to optimize the feeding rate of glycerol and the switching instants between the batch and feeding processes in the fermentation process, we propose a new nonlinear dynamical system to formulate the process. In...